Published date: December 18, 2025
Obstructive sleep apnea (OSA) is a chronic condition affecting millions1, with significant consequences for cardiovascular health, neurocognitive function and quality of life. The standard of care, continuous positive airway pressure (CPAP) therapy, demonstrates clear benefits, yet long-term adherence remains a major challenge. Up to 50% of patients discontinue CPAP within five years2, and only a minority transition to alternative therapies.
As highlighted in recent work, effective OSA management must focus on minimizing “time to effective therapy” and maximizing “time on effective therapy” across the patient’s lifespan. Structured and dynamic follow-up, including regular evaluation cycles and a multi-layered assessment of therapy effectiveness (e.g., the S-O-S criteria)3, are essential for identifying patients who require therapy optimization or alternative treatment early and providing prompt, effective care.
Current reimbursement structures in many countries are built around short-term compliance thresholds. For example, the U.S. Centers for Medicare and Medicaid Services (CMS) 90-day rule and similar policies in other health care systems incentivize early adherence but may inadvertently penalize gradual, individualized progress.4 These frameworks risk excluding patients who could benefit from therapy and reinforce health inequities.
As shown in recent analysis, only 1–2% of patients who discontinue CPAP are transitioned to second-line therapies, despite high dropout rates.5 This gap highlights the need for structured, dynamic follow-up and payment models that support therapy optimization and alternative treatment pathways.
Countries such as France have implemented telemonitoring and pay-for-performance models that incentivize sustained CPAP usage and direct resources toward patients at risk of discontinuation. In Germany, digital health applications and expanded coverage for alternative therapies are steps toward more flexible, patient-centered care.8
However, successful implementation depends on robust digital infrastructure, interdisciplinary collaboration and ongoing evaluation of care models. Disease management programs (DMPs) for OSA, as proposed in recent literature, should integrate digital tools and may further enhance long-term outcomes.5
A recent statement from a European Respiratory Society (ERS) task force reviewed the evidence and efficacy of telemonitoring in OSA. The group concluded that telemonitoring could improve the access to care and increase adherence. However, they also noted that cost and possible compliance challenges need consideration.9 More research is required to explore not just the integration of digital solutions into current pathways, but also the implementation of actual changes to those pathways.
Adherence to OSA therapy is a function of system design, not just patient motivation. To improve long-term outcomes, reimbursement frameworks must evolve from short-term adherence gating to models that support flexible, individualized and sustainable care. Structured follow-up, early identification of suboptimal therapy and integration of alternative treatment options are essential. This requires close collaboration between professional societies, payers and industry stakeholders with a shared focus on improving outcomes. As demonstrated in recent studies, including our own, these strategies can extend “time on effective therapy” and reduce the burden of untreated OSA across the lifespan.
Holger Woehrle, MD, is one of two CEOs of the Ulm Lung Center, Germany, where he works in pulmonology and sleep practice. With extensive clinical experience spanning internal medicine, pneumology, and sleep-related breathing disorders, he is recognized for his work in advancing diagnostics and therapy as well as clinical management of obstructive and central sleep apnea. He is a highly regarded speaker and an active contributor to scientific publications and conferences both in Germany and internationally.
Pépin JL, et al. J Clin Med. 2021;10(5):936.
Camilo MR, et al. Sleep Med. 2014 Sep;15(9):1021-4.
Hwang D, et al. Sleep, Volume 48, Issue Supplement_1, May 2025, Page A310,
Arzt M, et al. Somnologie. 2025.
Kaye L, et al. Sleep. 2025; zsaf208.
Woehrle H, et al. ERJ Open Res. 2024 Feb 26;10(1):00424-2023.
Krefting D, et al. Somnologie. 2023;27:248–254
Verbraecken J, et al. Eur Respir J. 2025 Nov 25;66(5):2500557